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PDRN is one of the most talked-about ingredients in Korean skincare, and you can shop it here in a serum, an essence and a hydrogel mask. Our PDRN range brings together Medicube and VT Cosmetics, with formulas made for hydrated, smooth-looking skin. Browse the range below, or explore more Korean skincare ingredients to build out your routine.
PDRN stands for polydeoxyribonucleotide, a DNA-derived ingredient that has become a staple of K-beauty. In skincare it is most often sourced from salmon, although some formulas use a plant-derived version instead. The VT Cosmetics PDRN products, for example, use ginseng-derived PDRN. Brands formulate with it to support hydration, a firmer-looking feel and a smoother, more even-looking complexion.
As with any cosmetic ingredient, results vary from person to person. PDRN skincare is designed to care for the look and feel of your skin, and it is not a treatment for any skin condition.
The right format depends on where you want PDRN in your routine. The Medicube PDRN Pink Peptide Serum pairs Salmon PDRN with peptides and is designed to firm, brighten and soothe sensitive skin. If you prefer a lighter step, the VT Cosmetics PDRN Essence 100 is a firming essence made to hydrate and support the skin barrier. For a boost on days when your skin feels tired, the VT Cosmetics PDRN Hydrogel Mask is a hydrogel sheet mask designed to hydrate, brighten and firm.
Serums and essences suit everyday routines, while a mask works well as an occasional extra. If you are new to this ingredient, start with one product and see how your skin responds before adding more.
Apply PDRN products to clean skin after your toner or essence and before your moisturiser, and always follow the directions on the pack. Patch test any new product first, especially if your skin is sensitive, and introduce one new product at a time. Finish your morning routine with sunscreen, as you would with any skincare routine. For more steps to layer in, browse our Korean serums, ampoules and emulsions.






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